DESCRIPTION

Koldec-Plus Tablet (Aceclofenac 100 mg, Paracetamol 325 mg, Cetirizine HCl 10 mg, Phenylephrine HCl 5 mg, Caffeine 25 mg) is a combination medicine used for the relief of symptoms associated with the common cold, flu, and allergies. It helps reduce pain, fever, nasal congestion, sneezing, and watery eyes. Koldec-Plus Tablet (Aceclofenac 100 mg, Paracetamol 325 mg, Cetirizine HCl 10 mg, Phenylephrine HCl 5 mg, Caffeine 25 mg) combination works by relieving inflammation, blocking allergic reactions, and reducing nasal blockage, providing effective symptomatic relief.

INDICATION

• Pain Relief: Koldec-Plus Tablet (Aceclofenac 100 mg, Paracetamol 325 mg, Cetirizine HCl 10 mg, Phenylephrine HCl 5 mg, Caffeine 25 mg) helps relieve mild to moderate pain such as headache, body ache, toothache, and musculoskeletal pain.

 

• Anti-inflammatory: Koldec-Plus Tablet (Aceclofenac 100 mg, Paracetamol 325 mg, Cetirizine HCl 10 mg, Phenylephrine HCl 5 mg, Caffeine 25 mg) helps reduce inflammation and swelling associated with conditions like arthritis or other musculoskeletal disorders.
 

• Decongestion: Koldec-Plus Tablet (Aceclofenac 100 mg, Paracetamol 325 mg, Cetirizine HCl 10 mg, Phenylephrine HCl 5 mg, Caffeine 25 mg) helps relieve nasal congestion and sinus pressure caused by common cold, sinusitis, or allergic rhinitis.
 

• Allergy Relief: Koldec-Plus Tablet (Aceclofenac 100 mg, Paracetamol 325 mg, Cetirizine HCl 10 mg, Phenylephrine HCl 5 mg, Caffeine 25 mg) helps reduce allergic symptoms such as sneezing, runny nose, itching, and watery eyes.
 

• Fatigue and Stimulation: Koldec-Plus Tablet (Aceclofenac 100 mg, Paracetamol 325 mg, Cetirizine HCl 10 mg, Phenylephrine HCl 5 mg, Caffeine 25 mg) helps improve alertness and may enhance the effectiveness of pain relief medicines.

MECHANISM OF ACTION

Aceclofenac (100 mg): Aceclofenac is a nonsteroidal anti-inflammatory drug (NSAID) that works by inhibiting cyclooxygenase enzymes (COX-1 and COX-2). This reduces the production of prostaglandins responsible for pain, inflammation, and fever.

 

Paracetamol (325 mg): Paracetamol works mainly in the central nervous system and reduces pain and fever by inhibiting prostaglandin synthesis in the brain.

 

Cetirizine HCl (10 mg): Cetirizine is a second-generation antihistamine that blocks H1 receptors and helps relieve allergic symptoms such as sneezing, runny nose, and watery eyes.

 

Phenylephrine HCl (5 mg): Phenylephrine acts as a nasal decongestant by constricting blood vessels in the nasal passages, which helps reduce swelling and nasal blockage.

Caffeine (25 mg): Caffeine is a mild central nervous system stimulant that helps improve alertness and may enhance the effectiveness of pain-relieving medicines.

DRUG INTERACTIONS

Drug-Drug Interactions: Koldec-Plus Tablet (Aceclofenac 100 mg, Paracetamol 325 mg, Cetirizine HCl 10 mg, Phenylephrine HCl 5 mg, Caffeine 25 mg) may interact with MAO inhibitors (isocarboxazid, linezolid, methylene blue, moclobemide, phenelzine, procarbazine, rasagiline, safinamide, selegiline, and tranylcypromine), cough medicines containing codeine or hydrocodone, and sedatives such as alprazolam, lorazepam, or zolpidem.

Drug-Food Interactions: Consumption of alcohol may increase the risk of side effects.

 

Drug-Disease Interactions: Koldec-Plus Tablet (Aceclofenac 100 mg, Paracetamol 325 mg, Cetirizine HCl 10 mg, Phenylephrine HCl 5 mg, Caffeine 25 mg) should be used with caution in patients with asthma, high blood pressure, heart disease, or hyperthyroidism.

SIDE EFFECTS OF KOLDEC-PLUS TABLET

Major & minor side effects for Koldec-Plus Tablet

• Dizziness
• Trouble sleeping
• Anxiety
• Mood changes
• Dry mouth

 

PRECAUTION

Koldec-Plus Tablet (Aceclofenac 100 mg, Paracetamol 325 mg, Cetirizine HCl 10 mg, Phenylephrine HCl 5 mg, Caffeine 25 mg) should be used with caution in patients with a history of NSAID intolerance, gastrointestinal disorders, or sensitivity to NSAIDs. It should also be used carefully in patients with liver disease, high blood pressure, heart disease, or thyroid disorders. Individuals who are sensitive to caffeine or suffering from anxiety or sleep disorders should limit caffeine intake while using this medicine.

DISCLAIMER

The information on this website is provided for general informational purposes only and is not medical advice. It is not a substitute for professional medical advice, diagnosis, or treatment. Consult a qualified healthcare provider for personalized advice. We do not endorse any specific products, treatments, or services mentioned.