DESCRIPTION

Cilon-TZ Injection (Ceftriaxone 1000 mg + Tazobactam 125 mg) contains two antimicrobial agents, ceftriaxone and tazobactam. This medication is used for the treatment of bacterial infections affecting different parts of the body such as the skin, urinary tract, nose, throat, and lungs. Cilon-TZ Injection (Ceftriaxone 1000 mg + Tazobactam 125 mg) is also administered to help prevent bacterial infections at surgical sites. The medicine works by interfering with the formation of the bacterial cell wall, which leads to the destruction of bacteria and helps control the infection.

INDICATION

• Bacterial infections: Cilon-TZ Injection (Ceftriaxone 1000 mg + Tazobactam 125 mg) is used to treat various bacterial infections including infections of the urinary tract, bones and joints, skin, and other tissues. Cilon-TZ Injection (Ceftriaxone 1000 mg + Tazobactam 125 mg) helps control infections caused by bacteria by stopping their growth and spread.

• Lower respiratory tract infection: Cilon-TZ Injection (Ceftriaxone 1000 mg + Tazobactam 125 mg) is used in the treatment of bacterial infections of the lower respiratory tract. Cilon-TZ Injection (Ceftriaxone 1000 mg + Tazobactam 125 mg) helps manage infections affecting the lungs and bronchial tubes by eliminating the bacteria responsible for the infection.

• Intra-abdominal Infection: Cilon-TZ Injection (Ceftriaxone 1000 mg + Tazobactam 125 mg) is used to treat bacterial infections occurring within the abdominal area. These infections can involve organs and tissues present inside the abdomen and require antimicrobial treatment to control the spread of bacteria.

MECHANISM OF ACTION

• Ceftriaxone: Ceftriaxone is a cephalosporin antibiotic that works by inhibiting the synthesis of the bacterial cell wall. It binds to penicillin-binding proteins present in bacteria and prevents the formation of the cell wall structure. This weakens the bacterial cell wall and eventually leads to the death of the bacteria.

• Tazobactam: Tazobactam acts as a beta-lactamase inhibitor. Some bacteria produce beta-lactamase enzymes that can break down certain antibiotics and reduce their effectiveness. Tazobactam blocks these enzymes and protects ceftriaxone from being destroyed, allowing the antibiotic to remain active against bacteria.

DRUG INTERACTIONS

• Drug-Drug Interaction: Cilon-TZ Injection (Ceftriaxone 1000 mg + Tazobactam 125 mg) may interact with medications used to reduce uric acid levels such as probenecid, neuromuscular blocking agents such as vecuronium, anticancer medicines such as methotrexate, diuretics such as furosemide, antibiotics including chloramphenicol, gentamicin, and streptomycin, and blood-thinning medicines such as heparin.

• Drug-Food Interaction: No interaction found.

• Drug-Disease Interaction: Inform your doctor if you have kidney problems, liver problems, blood-related disorders, kidney stones, or digestive system disorders before using this medication.

SIDE EFFECTS OF CILON TZ INJECTION
Major & minor side effects for Cilon TZ Injection

• Nausea
• Vomiting
• Fever
• Dizziness

PRECAUTIONS

Important precautions when using Cilon-TZ Injection (Ceftriaxone 1000 mg + Tazobactam 125 mg) include monitoring kidney and liver function during treatment and checking for possible hypersensitivity to penicillin or cephalosporin antibiotics due to potential cross-reactivity. The medication should be used carefully with calcium-containing solutions and with anticoagulant medicines. Monitoring for antibiotic-associated infections and observing the injection site for local reactions is also recommended. Regular medical supervision is advised during prolonged therapy.

DISCLAIMER

The information on this website is provided for general informational purposes only and is not medical advice. It is not a substitute for professional medical advice, diagnosis, or treatment. Consult a qualified healthcare provider for personalized advice. We do not endorse any specific products, treatments, or services mentioned.